An HTTP subdomain refers to a subdivision of a domain name that is designated to handle a specific HTTP request. It is a domain name that is a subset of a larger domain, indicated by a prefix or subdomain name, such as “www” in the URL “www.example.com.” The HTTP protocol uses subdomains to allow websites to have multiple web servers or to divide content into different sections of a website. For example, a company may use “blog.example.com” for their blog and “store.example.com” for their online store.