Securing your JavaScript application involves various practices to protect the application from potential threats or vulnerabilities. Here are some ways:
1. Implement Content Security Policy (CSP): This is an effective way to prevent Cross-Site Scripting (XSS) attacks by controlling resources the user agent is allowed to load for a given webpage.
1. Use HTTPOnly cookies: These are not accessible via JavaScript and hence immune to XSS attacks.
1. Input Validation: Always validate user inputs and where possible, use validation libraries.
1. Escape Output: All dynamic content must be correctly escaped. This differs according to where in the document the content is being inserted.
1. Encrypt sensitive data: Always encrypt sensitive data like passwords both on client and server end.
1. Use HTTPS: Always use secure connections for your web application. HTTPS ensures the privacy and integrity of data while being transmitted over the internet.
1. Code Auditing: Ensure to perform regular code audits and review previously written codes to find or fix any possible security issues.
1. Ensure Up-To-Date: Always update the JavaScript libraries. Out-of-date libraries can potentially create room for attacks.
1. Use of Anti-Malware: Apply appropriate anti-malware software which can help protect your JavaScript code.
1. Use Secure APIs: APIs must follow the same security protocols. Avoid exposing any sensitive information through your APIs.
1. Use Web Tokens: JWT (JSON Web Tokens) can secure communications between users and servers.
1. Deploy CORS: Enable Cross-Origin Resource Sharing only with trusted sites. It restricts the requests of JavaScript to access different domain than it’s origin.
1. Limit the execution of JavaScript: Use sandboxing or iframe methods where you need to control the execution of JavaScript.
Remember, while these practices can significantly reduce the risk, they cannot completely eliminate all threats due to the evolving nature of the security threats. It’s about risk management and having the appropriate levels of security in place for the types of data you handle.