Integrating Bootstrap into a Node.js application requires npm (node package manager) and involves several steps:
Step 1: Setup your node.js app:
Select a project folder and initialize a node.js project from terminal by running
```
$ npm init
```
Follow the prompt to setup your application.
Step 2: Install Express
Express is a web application framework for Node.js. Install Express by running
```
$ npm install express —save
```
Step 3: Install Bootstrap
Bootstrap can be installed and managed via npm. Go to the root of your project directory and run
```
$ npm install bootstrap —save
```
This will download Bootstrap into the node\_modules folder in your project directory.
Step 4: Set up Express server
Create the main application file (commonly named as app.js) and set up Express server. The file contents might look like this:
```
var express = require(‘express’);
var app = express();
var path = require(‘path’);
// viewed at http://localhost:8080
app.get(‘/’, function(req, res) {
res.sendFile(path.join(__dirname + ‘/index.html’));
});
app.listen(8080);
```
Step 5: Create an HTML File
Create an index.html file in your main project directory.
```
Step 6: Run your server
Run your server by typing the following command in your terminal:
```
$ node app.js
```
Then, open a browser and go to http://localhost:8080 to view your Bootstrap-styled page!
Remember to add node\_modules/ in your .gitignore file to prevent your local modules from being installed on your server. Instead, depend on your package.json to inform the server which packages to install.